Biodefend EP
Biodefend EP
INCI: Phenoxyethanol (and) Ethylhexylglycerin
Category: Preservative
Trade name: Biodefend EP
CAS number: 122-99-6, 70445-33-9
1. Description
- Biodefend EP is a liquid cosmetic preservative based on phenoxyethanol and ethylhexylglycerin. The addition of ethylhexylglycerin affects the interfacial tension at the cell membrane of microorganisms, improving the preservative activity of phenoxyethanol.
- Biodefend EP has a broad, balanced spectrum of effects against bacteria, yeast, and mold fungi.
- Biodefend EP can be considered safe for the preservation of cosmetics and toiletries.
2. Composition
|
INCI Name |
CAS No. |
|
Phenoxyethanol |
122-99-6 |
|
Ethylhexylglycerin |
70445-33-9 |
3. Characteristics
| Specifications |
Typical value for guidance |
|
Appearance |
Colorless Liquid |
|
Assay |
99.5 |
|
Water solubility (20°C) |
approx. 10 g/l (at 60°C approx. 15 g/l) |
|
Density (20°C) |
approx. 1.09 g/ml |
|
Phenol |
Max. 10 ppm |
|
Odor |
Characteristic |
4. Microbiological effectiveness
- Biodefend EP is equally effective against bacteria, yeast and mold fungi. It is a typically biostatic product with the biocidal properties necessary for practical use.
- For Biodefend EP to perform effectively in destroying organisms in products already contaminated a minimum contact time of 48 hours is necessary. Since the effect of Biodefend EP takes place through chemical reactions with the microorganisms when it is used in heavily contaminated products loss of active ingredient must be taken into account.
- Good production hygiene as well as the use of raw materials with low microorganism levels as a result of correct raw material control are of course vital prerequisites for the production of microbiologically faultless finished products.
- Biodefend EP is proven to have better efficacy against many microorganisms than phenoxyethanol alone. Germ count reduction test. Dilutions of Biodefend EP are prepared with sterile tap water. 50 ml portions of the end solutions are each inoculated with 0.5 ml microorganism suspension (initial microorganism count approx. 108 (cfu/ml) and stirred.
- These solutions are streaked out onto tryptone soya agar or Sabouraud-dextrose 4 % agar after 3, 6, 24, 48, 72 and 168 hours depending on the test organism. The cultures are incubated for 48 hours at 37°C, except for Aspergillus niger, which is incubated for 72 hours at 25 – 27°C.
- The evaluation is made on the basis of a semi-quantitative assessment of the microbial growth of the streaks.
5. Example of use
- Benefit
- Global approvals as a preservative for cosmetics.
- Effective control against a broad range of bacteria.
- Excellent performance when used in combination with a wide range of preservatives and fungicides.
- Compatible with most personal care ingredients.
- Will not impart unwanted color to a finished product.
- Biodefend EP is stable to hydrolysis, temperature, and pH. As a result of the good solubility of Biodefend EP, an easy dispersion in the various systems even at low temperatures is possible. Biodefend EP is effective in pH ranges up to 12.
- Function: Preservative
- Application:
- Dosage:
Leave-on/ Rinse off: 0.5- 1%. - Biodefend EP shows no interaction with pigments, such as TiO2.
6. Packing and storge:
Preservative should be stored at temperatures below 30°C (86°F).
Containers should not be exposed to direct sunlight. Storage conditions should also be in conformance with applicable legal, fire, and insurance regulations.
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